PerioGlas®
is the periodontal bone grafting material of choice for
clinicians around the world because of its ability to
predictably regenerate bone for patients and its ease of use for
dentists, periodontists, and oral surgeons.
For
a variety of Oral Osseous Defects
| Infrabony Defects |
Extraction Sites |
Intraosseous Flaws |
Traumatic Defects |
| Endodontic-peridontic Lesions |
Ridge Augmentation |
Periapical Defects |
Cystic Defects |
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| This
USBiomaterials surface-active bone-grafting
product accelerates the repair and regeneration
of the alveolar bone lost to periodontal
disease. The company has received FDA
clearance for indications including Infrabony
defects, Ridge Augmentation procedures, Ridge
Preservation, Filling Extraction Sockets,
Alveolar defects, Peri-apical Cysts and
Implants. It is activated in the presence of
water, saline or the patient's blood. PerioGlas®
can be sculpted by the clinician as needed to
confirm to the defect. |
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| SEE AND FEEL THE DIFFERENCE |
With PerioGlas, see rapid, predictable and long lasting bone regeneration in your patients. Also see the other beneficial clinical properties of PerioGlas :
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Improves periodontal attachment1,5,7
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Is hemostatic-reduces bleeding1,2,4,5
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Is completely biocompatibel-no risk of rejection6
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Is 1000 % synthetic-no risk of viral transfer6
FEEL THE DIFFERENCE
Feel the difference when working with PerioGlas, because no other bone graft material is easier to work with. It mixes easily in seconds; it adheres to instruments fro easy insertion; and it contours easily to the shape of the defects. Its negatively charged particles adhere to the defect site, so it does not float out, and you can even suction adjacent to the graft site!2,4
| Predictable Bone Regeneration |
Case Study :
Periodontal Defect
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Patient presents with severe periodontitis of mandibular second premolar. Pocket depth is 9mm |
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The periodontal osseous defect is debrided and decorticated prior to PerioGlas placement. This infrabony lesion presents as a two-or three-wall defect.
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PerioGlas is placed into the defect with minimal
bleeding noted. Papilla retention is necessary for
primary closure.
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At 24 months post-operative with no gingival bleeding on probing, pocket depth is reduced to
3mm. |
Thanks to Dr. Sam Low, Associate Dean & Professor of Periodontology, University Of Florida College of Dentistry, for this case and the one above.
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| Why clinicians all over the world are choosing PerioGlas® |
PerioGlas® eliminates the need for the second surgical site needed with autografting, reducing infection risk and patient discomfort. It also saves operating room time and cost.
PerioGlas® generates new bone just as fast as demineralized freeze dried bone
allograft8 while it eliminates concerns over viral
transmission6, and is easier to work with in-situ. PerioGlas generates predictable results since the variability of osteogenic potential between donors is eliminated.
PerioGlas® is more readily accepted by patients than animal derived products, and offers no risk of transgenic disease or
rejection6.
PerioGlas® is clinically shown to generate faster and denser bone growth than Hydroxyapatite and Tricalcium
Phosphate1,3. Also easier to work with in-situ, where it packs easily and stays in
place3. It also reduces the epithelial downgrowth typically seen with these products1.
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| PROVEN RESULTS |
Case Study :
Periodontal Defect
Pre-operative radiograph demonstrates severe osseous resorption
Post-operative radiograph 24 months following PerioGlas grafting. Evidence of significant bony fill in defect site.
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| Rapid and Lasting Bone Regeneration |
Case Study : Post Extraction Ridge Preservation

Pre-operative radiograph of lower right first molar with advanced alveoolar bone loss and a class III furcation defect due to periodontal disease.
The tooth was extracted and the defect site filed with
PerioGlas. This four-month follow-up radiograph shows progressive bone formation in the graft site.
Four-year follow-up
radiograph shows that the height and the contour of the new alveolar bone formed in the graft site is stable.
Thanks to Dr. King Smith for this case. Dr. Smith is chairman of Dept. of Oral and Maxillofacial Surgery at Fallston General Hospital, Maryland, U.S.A |
| The PerioGlas® Bioactive Process |
Case Study : A Single Particle in-situ
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Upon contact with physiological
fluids(i.e. blood), ions are exchanged and silica gel layer begins to form. It is this silica gel layer that promotes accelerated bone formation and differentiates PerioGlas® from other synthetic bone graft materials.
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Hydroxy-carbonate-apatite layer quickly develops and cannot be distinguished from the natural apatite of bones and teeth. Cells produce collagen fibers which bond the particles to the bone.
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Osteoblasts proliferate along the particle and begin to lay down new bone. This process begins in as little as two days.
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The regeneration process is complete in a matter of months, producing healthy, vascularized bone. Small amounts of residual PerioGlas® may remain present.
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References |
| • |
Wilson J, low
Sb.J. App Biomat. 1992;3:123-129 |
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Fetner AE, Hertigan MS, Low SB. Compend Cont Educ Dent. 1994:15(7): 932,935-938 |
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Oonishi H, Kuthitani S Yasukawa E et al. Clinical Orthopedics and Related Research. 1997;334:316-325 |
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Shapoff CA, Alexander DC , Clark AE. Compen Cont Educ Dent. 1997;18(4):359-367 |
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Low SB, King CJ, Kreiger
J.J. Int J Periodont Rest Dent.. 1997;17:359-367 |
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Quinones CR, Lovelace TB. Pract Periodont Aesthet Dent. 1997;9(7) 1-7 |
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Froum
SJ, Weinberg MA, Tarnow D." Comparison of Bioactive Glass and Open
Debridement." J
Periodontol. 1998;68:698-709 |
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Lovelace TB, Mellonig JT, Meffert
RM, et al. " Treatment of Periodontal Defects with Bioactive Glass" accepted for publication J Periodontal, scheduled Fall 1998 |
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